Not too long ago, experts in cryotechniques strictly denied that a cell could truly be vitrified, i.e. Countless mishaps, however, have taught electron microscopists that cryotechniques too are neither simple nor necessarily more life-like in their outcome. Thus, the result should be more life-like than after poisoning, tanĀ ning and drying a living cell as we may rudely call the conventional preparation of specimens for electron microscopy. At first glance, it seems as simple as it is attractive: the dynamics of life are frozen in, nothing is added and nothing withdrawn except thermal energy. To preserve tissue by freezing is an ancient concept going back preĀ sumably to the practice of ice-age hunters.
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